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Figure 5 | Genome Medicine

Figure 5

From: Isoform level expression profiles provide better cancer signatures than gene level expression profiles

Figure 5

Hierarchical clustering dendrograms and heat map based on core transcript and gene expression and the gene network for the core genes. The hierarchical clustering dendogram of 160 samples and heat map of gene-expression estimates of (A) 18 core transcripts and (B) 14 core genes that were significantly enriched in the top 5 gene networks identified by Ingenuity Pathway Analysis (IPA). The 18 transcripts were those having the maximum coefficient of variation (CV) values of all the core isoforms, representing 14 core genes. (C) IPA gene network of the 14 core genes, of which 12 belong to the canonical pathway with associated known functions in hematological system development and function, tissue morphology, and cellular development (in red).

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