Assessing biomarkers for brain diseases: progress and gaps

Table 1 Examples of consortia focused on enabling replication of brain biomarkers in multi-site studies

Consortia	Disorder	Protocols	Data analysis
BioMS-eu	MS	CSF collection, processing and biobanking	Standardized reporting
AddNeuroMed	AD, MCI	MRI acquisition MRI quality control	Automated analysis techniques
Parkinson's Progression Markers Initiative	PD	CSF and plasma collection and biobanking MRI, DTI acquisition	Standardized data collection and processing

AD, Alzheimer's disease; MCI, mild cognitive impairment; MS, multiple sclerosis; PD, Parkinson's disease. Charlotte Teunissen (VU Medical Center, Netherlands) reported on BioMS-eu, Simon Lovestone (Kings College London, UK) reported on AddNeuroMed, and Kenneth Marek (Institute for Neurodegenerative Disorders, USA) reported on the Parkinson's Progression Markers Initiative.

ISSN: 1756-994X