Name | Source | Positives | Negatives | N positives | N negatives |
---|---|---|---|---|---|
COSMIC2+/1 | COSMIC | Mutations that appear in 2 or more samples | Mutations that appear in 1 sample | 4,012 | 39,854 |
COSMIC5+/1 | COSMIC | Mutations that appear in 5 or more samples | Mutations that appear in 1 sample | 1,480 | 39,854 |
COSMIC2+/Pol | COSMIC/ HumVar [2] | Mutations that appear in 2 or more samples | Known polymorphisms | 4,012 | 8,257 |
COSMIC5+/Pol | COSMIC/ HumVar | Mutations that appear in 5 or more samples | Known polymorphisms | 1,480 | 8,257 |
COSMICD/O | COSMIC | COSMIC mutations included in the manually curated list of drivers used to train CHASM [5] | COSMIC mutations without the positive subset | 2,185 | 41,681 |
COSMICD/Pol | COSMIC/ HumVar | Mutations included in the manually curated list of drivers used to train CHASM | Known polymorphisms | 2,185 | 8,257 |
COSMICCGC/ nonCGC | COSMIC | COSMIC mutations in genes included in the Cancer Gene Census [13] | Non-recurrent COSMIC mutations in genes not included in the Cancer Gene Census | 4,685 | 35,907 |
WG2+/1 | Pooled cancer somatic mutations | Mutations that appear in 2 or more samples | Mutations that appear in 1 sample | 1,031 | 26,025 |
WGCGC/ nonCGC | Pooled cancer somatic mutations | Mutations in genes included in the Cancer Gene Census [13] | Non-recurrent mutations in genes not included in the Cancer Gene Census | 1,412 | 24,837 |