From: Getting personalized cancer genome analysis into the clinic: the challenges in bioinformatics
Name | Details | URL |
---|---|---|
ChEBI (Chemical Entities of Biological Interest) | Contains more than half a million chemical compounds classified according to their biological activity | |
DrugBank | Contains detailed chemical, pharmacological and pharmaceutical data linked with information on the sequence, structure and pathways of potential targets. The database contains information on almost 500 drugs | |
Resources from Peer Bork's group, including STITCH, SuperDrug, SuperNatural and SuperTarget/Matador | Bork's group has developed a number of systems that help link drugs to their protein and genomic targets, including data on adverse drug effects and symptoms | |
PharmGKB | Repository linking genomic information on 2,500 genetic variants with clinical data derived from pharmacogenomics studies, and the corresponding diseases and phenotypes | |
TTD (Therapeutic Target Database) | Contains data for relations between 2,000 targets and more than 15,000 drugs, including information extracted from clinical trials |