Table 3 Stroke odds ratio for E-alone and E+P, by genotype of SNPs in F13A1 region

From: Exploring the interaction between SNP genotype and postmenopausal hormone therapy effects on stroke risk

		SNP genotype
	Number of cases	GG		GA		AA
		OR	95% CI	OR	95% CI	OR	95% CI	p-2df	p-1df
rs2154299
E-alone
All	351	1.372	(1.086, 1.732)	0.920	(0.547, 1.548)	0.511	(0.094, 2.791)	0.21471	0.08111
Ischemic	263	1.614	(1.226, 2.124)	1.022	(0.566, 1.846)	0.682	(0.114, 4.079)	0.27045	0.10598
Hemorrhagic	48	0.756	(0.404, 1.414)	0.341	(0.069, 1.689)	NA	(NA, NA)	0.34339	0.34339
E+P
All	438	1.517	(1.218, 1.889)	0.685	(0.459, 1.023)	0.238	(0.027, 2.13)	0.00066	0.00013
Ischemic	319	1.553	(1.198, 2.013)	0.68	(0.426, 1.087)	0.238	(0.027, 2.13)	0.00229	5.00E-04
Hemorrhagic	76	1.199	(0.724, 1.988)	0.635	(0.226, 1.784)	NA	(NA, NA)	0.27362	0.27362
rs12194855
E-alone
All	351	0.682	(0.114, 4.079)	0.890	(0.532, 1.492)	1.372	(1.086, 1.732)	0.25707	0.10080
Ischemic	263	0.682	(0.114, 4.079)	1.022	(0.566, 1.846)	1.614	(1.226, 2.124)	0.27045	0.10598
Hemorrhagic	48	NA	(NA, NA)	0.341	(0.069, 1.689)	0.756	(0.404, 1.414)	0.34339	0.34339
E+P
All	438	0.238	(0.027, 2.130)	0.702	(0.471, 1.046)	1.509	(1.212, 1.88)	0.00097	2.00E-04
Ischemic	319	0.238	(0.027, 2.130)	0.703	(0.442, 1.118)	1.543	(1.190, 2.000)	0.00337	0.00076
Hemorrhagic	76	NA	(NA, NA)	0.635	(0.226, 1.784)	1.199	(0.724, 1.988)	0.27362	0.27362

OR, estimated intervention odds ratio. p-2df, P-value regressing randomization assignment on indicator for one or two minor alleles. p-1df, P-value regressing randomization assignment on number of minor alleles. NA indicates information (data) not available. CI, confidence interval.

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