Skip to main content

Table 1 Examples of categories of health effects stratified by age of onset

From: A personal perspective on returning secondary results of clinical genome sequencing

 

Recognized therapeutic or preventive intervention

Untreatable

Childhood onset

Biotinidase deficiency, pharmacogenomic variants

Tay Sachs disease

Adult onset

Breast cancer predisposition caused by mutations in BRCA1

Parkinson's disease caused by mutations in PARK1