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Figure 1 | Genome Medicine

Figure 1

From: Pharmacogenetics in type 2 diabetes: potential implications for clinical practice

Figure 1

Proposed tissue targets of the major classes of anti-diabetes medications. For details, see Table 2. Although the primary tissue targets are shown, many of these drugs have multi-organ effects. The dotted line denotes putative mechanisms that remain to be fully demonstrated in humans. DPP-IV, dipeptidyl peptidase-IV; GI, gastrointestinal tract; GLP-1, glucagon-like peptide-1; TZDs, thiazolidinediones.

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