Table 3 Breast cancer odds ratio for WHI trial interventions by genotype of MRPS3 0 SNP rs7705343

From: Genetic variants in the MRPS30 region and postmenopausal breast cancer risk

		SNP genotype
		GG		GA		AA
Intervention	Number of cases	OR^a	95% CI	OR^a	95% CI	OR^a	95% CI	P-value^b
E-alone	247	0.484	(0.306, 0.766)	0.974	(0.684, 1.387)	0.969	(0.508, 1.846)	0.043
E+P	471	1.404	(1.003, 1.965)	1.248	(0.966, 1.613)	1.303	(0.858, 1.980)	0.863
DMQ	428	0.524	(0.360, 0.761)	0.862	(0.651, 1.141)	1.023	(0.643, 1.627)	0.042
CaD	1,049	0.763	(0.613, 0.951)	1.071	(0.902, 1.271)	1.049	(0.791, 1.391)	0.046

^aOR, estimated intervention odds ratio; ^bP-value, significance level for SNP interaction with clinical trial intervention. CI, confidence interval; WHI, Women's Health Initiative.

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