Predicting treatment outcome in classical Hodgkin lymphoma: genomic advances

Table 5 Early predictors of response to chemotherapy in HL: interim PET and serum TARC levels

Factor	Number of patients	Significance, univariate	Significance, multivariate	Reference(s)
Interim PET	77	+ (PFS)	+ (PFS)	[26]
	260	+ (PFS)	+ (PFS)	[25]
	40	+ (PFS)	NA	[27]
TARC
Basal and after therapy	62	+ (OS, RR)	NA	[92]
After one cycle, mid and after treatment	63	+ (RR)	NA	[93]

The presence (+) or absence (-) of a significant correlation with the study endpoints is given.
NA, not applicable; OS, overall survival; PET, positron emission tomography; PFS, progression-fee survival; RR, response rate; TARC, thymus and activation-regulated chemokine.

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